Correlative firing patterns of serotonergic neurons in rat dorsal raphe nucleus
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چکیده
منابع مشابه
Correlative firing patterns of serotonergic neurons in rat dorsal raphe nucleus.
In this study, local neuronal interactions in the midbrain dorsal raphe nucleus (DRN) were analyzed by the use of autocorrelation and cross-correlation histograms. The autocorrelograms of serotonin (5-hydroxytryptamine; 5-HT)-containing cells showed an initial trough and subsequent periodicity which corresponded to their regular rhythmic firing pattern. Cross-correlograms revealed that all adja...
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Accumulating evidence suggest a reciprocal interaction between neurosteroids, especially 5alpha-pregnan-3alpha-ol,20-one (3alpha,5alpha-THP, allopregnanolone), and the serotonergic (5-HT) system. Both 5-HT and neurosteroids seem to play an important role in the pathophysiology of major depression. We have previously shown that a 7-d treatment with 3alpha,5alpha-THP drastically increases the spo...
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We studied the control of dorsal raphe (DR) serotonergic neurons by dopaminergic transmission in rat brain using microdialysis and single unit extracellular recordings. Apomorphine (0.5-3.0 mg/kg s.c.) and quinpirole (0.5 mg/kg s.c.) increased serotonin (5-HT) output in the DR and (only apomorphine) in striatum. These effects were antagonized by 0.3 mg/kg s.c. SCH 23390 (in DR and striatum) and...
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ژورنال
عنوان ژورنال: The Journal of Neuroscience
سال: 1982
ISSN: 0270-6474,1529-2401
DOI: 10.1523/jneurosci.02-01-00011.1982